Nature slumbers fitfully. Beware the day it wakes.
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This is of course not meant literally; I do not anthropomorphize nature. But that we cannot simply go on as we are should by now be apparent to all who have eyes to see: Nature is a web of incalculable complexity, rich and robust but not infinitely so.
How far off is the crucial tipping-point? The real danger lies in this: We have no idea.